Bone Marrow Transplant (BMT), Pediatric BMT at World Class Hospitals in India
Centre for Bone Marrow Transplant is the largest in India and among the biggest in Asia. A stand alone dedicated facility, equipped with ultra‐modern infrastructure and internationally trained, widely experienced faculty. The Centre is supported by state‐of‐the‐art laboratory services and transfusion services, along with a fully equipped radiation oncology unit with facility for total body irradiation.
In a short span of last few years, our affiliated BMT centre has done more than 500 transplants with > 80 Percent success rate. including India’s first Multiple Donor Transplant. Each BMT treatment room is supported by separate HEPA filter with triple level air filtration. Transplants are routinely performed for children as well as adults. The centre is credited with Delhi’s First MUD (Match Unrelated Donor) Transplant.
This is the only hospital with a dedicated 24 bed BMT unit with Pediatric ICUs and the back up of best in class radiation and medical oncology services.
The Centre offers both allogenic and autologous transplant using bone marrow, peripheral blood stem cells and cord blood stem cells for various benign and malignant disorders like Thalassemia, Aplastic Anaemia, Leukemia, Lymphomas, Multiple Myelomas and Advanced Paediatric Solid Tumors.
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What is Bone Marrow Transplant/Stem Cell Transplant?
Bone marrow transplantation (BMT/SCT) is a medical procedure being used to treat diseases once thought incurable. Bone marrow transplantation (also known as stem cell transplantation) involves harvesting healthy stem cells from the donor to replenish the bone marrow of the patient. The new stem cells take over the production of the blood cells. It is the transplantation of multi potent hematopoietic stem cells, usually derived from bone marrow, peripheral blood stem cells, or umbilical cord blood from donor to recipient.
Who requires Bone Marrow Transplant/Stem Cell Transplant?
Stem cell transplant is a curative treatment for various diseases:
- Thalassemia & Sickle cell disease.
- Aplastic anemia.
- Leukemia’s (ALL, AML, CML, CLL).
- Multiple myeloma.
- High grade lymphoma’s.
- Neuroblastoma.
- Wilm’s tumor.
- High grade sarcoma’s.
- Allogenic transplant (from a donor).
- Autologous transplant (from self)
- Allogeneic BMT involves using the stem cells of a donor.
- The donor may be a relative, usually a brother or sister, or an unrelated (anonymous) donor.
- The donor needs to be Histocompatible Leukocyte antigen (HLA) match.
- Sibling Donor Transplant
- Match Unrelated Donor.
- Haplo‐ identical Transplant.
- Cord Blood Transplant.
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Autologous BMT is done by using the patient’s own stem cells.
Indications of Autologous BMT
Acute Promyelocytic Leukemia
Multiple Myeloma
Hodgkins & Non Hodgkins Lymphoma
Germ Cell Tumor
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