Deep Brain Stimulation for Parkinsons Disease at Best Hospitals in India

Deep Brain Stimulation is widely used to alleviate tremor, rigidity and dyskinesia associated with a variety of movement disorders. The majority of DBS operations are carried out in patients with Parkinson’s disease (PD) and other neurological condition characterized by trembling. Most of successful effects have been achieved using DBS in the vicinity of the subthalamic nucleus (STN), a small but integral part of the basal ganglia, which collectively control complex movements. DBS has proved an extremely effective approach towards movement disorders: it can return the patient to a normal quality of life and allow them to play their full part in the family and in society. It is a reversible approach (the electrodes can be removed), and is therefore preferred to lesions (such as pallidotomy or thalamotomy).

Who are the candidates for Deep Brain Stimulation Therapy?

Patients with Parkinson’s disease, essential tremor, dystonia, epilepsy or tremor due to multiple sclerosis, with movement related symptoms that cannot be controlled by medications can be evaluated as possible candidates for deep brain stimulation only In addition, patients who experience intolerable side effects from medication may also be candidates. It should be noted that not everyone is eligible for DBS, patient’s mental state and general condition is taken into consideration. It is important to note that these issues should be discussed with a movement disorders expert or specially trained neurologist.

Dystonia does not respond to DBS in the same as other movement disorders do. For example, persons treated for tremor will generally improve within seconds of turning the generator on. In patients with dystonia, improvement may be delayed for days, and weeks or months may pass before the full extent of the benefit is reached. DBS does not necessarily eliminate the possibility of subsequent drug or botulinum toxin treatments.

Deep Brain Stimulation is most commonly used to Treat the Symptoms of these common Neurological Conditions:

Parkinson’s Disease Deep Brain Stimulation was approved by the Food and Drug Administration (FDA) to treat Parkinson’s disease in 2002 and is now a standard treatment for this condition. Over time, the symptoms associated with Parkinson’s, which include stiffness, slowness, and tremor, become resistant to the medication. The symptoms will fluctuate as the medications provide relief for only a few hours at a time. For these patients, deep brain stimulation can offer steady symptom control for 24 hours per day, to provide better quality of life.

Essential Tremor When patients have inadequate response to medication, deep brain stimulation is an option to effectively treat essential tremor. Research shows that medications often only elicits a response in about half of patients with essential tremor. However, patients who undergo deep brain stimulation can experience approximately 80 percent improvement in hand tremor.

Dystonia Dystonia is a condition in which patients experience involuntary muscle contractions that force parts of the body into abnormal postures. DBS has been FDA approved for this condition under what is known as the Humanitarian Device Exemption (HDE.) This means that DBS surgery can be done on those with debilitating dystonia that does not respond well to medication, and in whom dystonia is the only neurological condition.

Obsessive Compulsive Disorder (OCD) Deep brain stimulation has been approved by the FDA under the Humanitarian Device Exemption (HDE) for the treatment of obsessive compulsive disorder (OCD.)

Advantages of Deep Brain Stimulation

  • Deep brain stimulation is a relatively safe procedure.
  • The procedure can treat all the major symptoms of Parkinson’s disease.
  • Daily living tasks and quality of life are also improved.
  • With subthalamic nucleus stimulation, medications can usually be reduced.
  • The stimulator can also be turned off at any time if deep brain stimulation is causing excessive side effects.

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